Mapping-By-Sequencing

Project Overview N2 C. elegans were randomly mutated, and those that displayed a defective zap response were isolated. The genomes of five of the defective mutant strains were sent to be sequenced. In order to find the causative mutation in each, students are using Galaxy to determine the sequencing differences in comparison to the original…

Negative Valence Project

Project Overview The purpose of the Negative Valence assay is to provide additional evidence that C. elegans model a behavior akin to fear while exposed to alternating current. This assay will model associative learning, in which the worms will hopefully exhibit an aversive response to an attractive odor after being zapped while exposed to said…