Project Overview
A precipice response is a rapid reversal behavior when the head of the worm detects an edge. This response can provide insight into mechanosensation by observing sightless C. elegans and their FLP neuron. Additionally, previous studies have pointed out that the FLP neuron has a role in gentle vs. harsh touch sensations, such as triggering cliff avoidance behaviors. By testing worms with nonfunctional FLP neurons, we can determine whether or not the neurons play an important role in their precipice response.
Question
What role do proprioceptive neurons have in mechanosensation, and what is the involvement of those neurons in the precipice response in C. elegans?
Experimental Setup
Team
Natalie Chua, Ryan Duh, and Cheska Bagalso